Identification of microRNA targets for the alternative splicing isoforms of CD46.

• Main Author: Teo, Zhi Lin.
• Other Authors: School of Biological Sciences
• Format: Final Year Project
• Language: English
• Published: 2013
• Subjects: DRNTU::Science
• Online Access: http://hdl.handle.net/10356/52298
• Institution: Nanyang Technological University

CD46 is a transmembrane protein that is expressed on all nucleated host cells. Other than being involved in the complement pathway, defects in CD46 or CD46-mediated signals are also linked to human autoimmune diseases. Some tumor cells are found to overexpress CD46, suggesting its probable role in c...