Characterization of the regulation of CD46 alternative splicing

• المؤلف الرئيسي: Tang, Sze Jing
• مؤلفون آخرون: Xavier Roca
• التنسيق: Theses and Dissertations
• اللغة: English
• منشور في: 2016
• الموضوعات: DRNTU::Science::Biological sciences
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/65984
• المؤسسة: Nanyang Technological University

Alternative splicing gives rise to multiple mRNA and protein isoforms. This process is catalyzed by the spliceosome and regulated by cis-acting elements, trans-acting factors, transcription and chromatin structure. CD46 is a membrane-bound complement control protein with several extracellular STP do...