Characterization of the alternative splicing regulating the proapoptotic gene BIM.
Alternative splicing, regulated by cis-acting elements and trans-acting factors, enables the exons of the RNA produced by transcription of a gene to be reconnected in several ways, resulting in different mRNAs being produced. BCL2-homology domain 3 (BH3), essential for proapoptotic function of BIM,...
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Format: | Final Year Project |
Language: | English |
Published: |
2012
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Online Access: | http://hdl.handle.net/10356/49359 |
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Institution: | Nanyang Technological University |
Language: | English |