Characterization of the alternative splicing regulating the proapoptotic gene BIM.

• المؤلف الرئيسي: Lee, Qing Feng.
• مؤلفون آخرون: School of Biological Sciences
• التنسيق: Final Year Project
• اللغة: English
• منشور في: 2012
• الموضوعات: DRNTU::Science
• الوصول للمادة أونلاين: http://hdl.handle.net/10356/49359
• المؤسسة: Nanyang Technological University

Alternative splicing, regulated by cis-acting elements and trans-acting factors, enables the exons of the RNA produced by transcription of a gene to be reconnected in several ways, resulting in different mRNAs being produced. BCL2-homology domain 3 (BH3), essential for proapoptotic function of BIM,...