Identification of microRNA targets for the alternative splicing isoforms of CD46.

• المؤلف الرئيسي: Teo, Zhi Lin.
• مؤلفون آخرون: School of Biological Sciences
• التنسيق: Final Year Project
• اللغة: English
• منشور في: 2013
• الموضوعات: DRNTU::Science
• الوصول للمادة أونلاين: http://hdl.handle.net/10356/52298
• المؤسسة: Nanyang Technological University

CD46 is a transmembrane protein that is expressed on all nucleated host cells. Other than being involved in the complement pathway, defects in CD46 or CD46-mediated signals are also linked to human autoimmune diseases. Some tumor cells are found to overexpress CD46, suggesting its probable role in c...