Functional characterization of ikk2 zebrafish mutants and TALEN-mediated genetic screen of camel mutants.

• Main Author: Chua, Yun Yu.
• Other Authors: Vladimir Korzh
• Format: Final Year Project
• Language: English
• Published: 2013
• Subjects: DRNTU::Science
• Online Access: http://hdl.handle.net/10356/52696
• Institution: Nanyang Technological University

IKK2 (IKK-β) is a master regulator of the NF-κB signaling pathway, which regulates a wide range of cellular activities. Although tremendous amount of work has been carried out to study its function in immunology, cell differentiation/proliferation, apoptosis, and cancer progression; the role of IKK2...