OncomiR-138 targets genes involved in senescence and its inhibition induces growth arrest of malignant gliomas.
Glioblastoma Multiforme (GBM) is the most aggressive types of brain cancer with a median lifespan of 12 months. Recent studies have reported elevated expression of miR-138 in Glioma Stem cells (GSCs) and demonstrated that knocking miR-138 down prevented tumor progression, though the exact downstream...
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| Format: | Final Year Project |
| Language: | English |
| Published: |
2013
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| Online Access: | http://hdl.handle.net/10356/52897 |
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| Institution: | Nanyang Technological University |
| Language: | English |