Dysregulation of dopamine metabolism in LRRK2-associated Parkinson's disease.
Background: Parkinson’s disease (PD) is a common, age-related, progressive and debilitating neurodegenerative disorder. Mutations in Leucine Rich Repeat Kinase 2 gene (LRRK2) are the cause of familial and sporadic PD. The pathophysiological role of LRRK2 in PD remains unclear. Our preliminary data s...
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Format: | Final Year Project |
Language: | English |
Published: |
2013
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Online Access: | http://hdl.handle.net/10356/52902 |
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Institution: | Nanyang Technological University |
Language: | English |