Dysregulated dopamine metabolism in LRRK2 mutants
Background: LRRK2 mutations are the most common genetic cause of Parkinson’s disease (PD). Previously, a compelling link between dopamine metabolic dysregulation and PD pathogenesis has been established. Specifically, dopamine synthesis enzymes were reportedly down-regulated in LRRK2 mutants G2019S...
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| Format: | Final Year Project |
| Language: | English |
| Published: |
2015
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| Online Access: | http://hdl.handle.net/10356/63629 |
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| Institution: | Nanyang Technological University |
| Language: | English |