Dysregulation of L-arginine metabolism and bioavailability associated to free plasma heme

Severe Plasmodium falciparum malaria is associated with hypoargininemia, which contributes to impaired systemic and pulmonary nitric oxide (NO) production and endothelial dysfunction. Since intravascular hemolysis is an intrinsic feature of severe malaria, we investigated whether and by which mechan...

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Bibliographic Details
Main Authors: F. Omodeo-Salè, L. Cortelezzi, Z. Vommaro, D. Scaccabarozzi, A. M. Dondorp
Other Authors: Universita degli Studi di Milano
Format: Article
Published: 2018
Subjects:
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/28674
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Institution: Mahidol University