Determination of intracellular calcium inhibition effect and cytotoxocity of engineered Bradykinin antagonists.

• Main Author: Tan, Junus Jun Rong.
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Final Year Project
• Language: English
• Published: 2013
• Subjects: DRNTU::Engineering::Bioengineering
• Online Access: http://hdl.handle.net/10356/53682
• Institution: Nanyang Technological University

Chronic pain is a physiological issue universally associated with many medical conditions, severe injuries and major surgeries. Bradykinin (BK) and kallidin (KD) are short-term peptidic mediators that double as potent endogenous pain inducers. Jointly known as kinins, their releases occur during tis...