The role of mTORCs signaling in endothelial cell migration.

• Main Author: Liu, Shiyang.
• Other Authors: Koh Cheng Gee
• Format: Final Year Project
• Language: English
• Published: 2013
• Subjects: DRNTU::Science::Biological sciences::Molecular biology
• Online Access: http://hdl.handle.net/10356/53794
• Institution: Nanyang Technological University

The Mammalian target of rapamycin (mTOR) is a serine/ threonine kinase that functions as two distinct complexes, mTORC1 and mTORC2. Both of them have been shown to be involved in cell migration via different downstream effectors, among which Rho-family small GTPases play crucial roles. Endothelial c...