Genetic analysis of SCA8 trinucleotide repeats in Parkinson's disease.

• Main Author: Lin, Cynthia XinTian.
• Other Authors: School of Biological Sciences
• Format: Final Year Project
• Language: English
• Published: 2013
• Subjects: DRNTU::Science
• Online Access: http://hdl.handle.net/10356/53805
• Institution: Nanyang Technological University

Trinucleotide repeats have attracted special interest due to their involvement in human neurodegenerative disorders known as the triplet repeat expansion diseases, such as the Spinocerebellar ataxia (SCA). Different SCA subtypes such as SCA3, SCA17 and SCA8 appears to be associated with Parkinsonism...