Improvement on geometry and hemodynamics of coronary artery bypass grafting : numerical and experimental studies

Improvement on geometry and hemodynamics of coronary artery bypass grafting : numerical and experimental studies

Impaired local hemodynamics associated with unfavorable anastomotic geometry has been implicated in the initiation and progression of intimal hyperplasia and atherosclerosis, the two vascular diseases for failing bypass anastomoses. Focused on the distal coronary anastomosis, this thesis seeks to de...

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Main Author: Xiong, Fangli
Other Authors: Chong Chuh Khiun
Format: Theses and Dissertations
Published: 2008
Subjects:
DRNTU::Engineering::Mechanical engineering::Surgical assistive technology
Online Access:https://hdl.handle.net/10356/5424
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Institution: Nanyang Technological University
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spelling sg-ntu-dr.10356-54242023-03-11T17:43:58Z Improvement on geometry and hemodynamics of coronary artery bypass grafting : numerical and experimental studies Xiong, Fangli Chong Chuh Khiun School of Mechanical and Aerospace Engineering DRNTU::Engineering::Mechanical engineering::Surgical assistive technology Impaired local hemodynamics associated with unfavorable anastomotic geometry has been implicated in the initiation and progression of intimal hyperplasia and atherosclerosis, the two vascular diseases for failing bypass anastomoses. Focused on the distal coronary anastomosis, this thesis seeks to determine critical hemodynamic wall parameters that indicate disease-susceptible sites as well as to optimize anastomotic geometry and hemodynamics pertaining to long-term graft viability. Numerical simulation and in vitro experimentation using Particle Image Velocimetry were employed to study pulsatile flows in coronary anastomotic models. DOCTOR OF PHILOSOPHY (MAE) 2008-09-17T10:50:13Z 2008-09-17T10:50:13Z 2007 2007 Thesis Xiong, F. L. (2007). Improvement on geometry and hemodynamics of coronary artery bypass grafting : numerical and experimental studies. Doctoral thesis, Nanyang Technological University, Singapore. https://hdl.handle.net/10356/5424 10.32657/10356/5424 Nanyang Technological University application/pdf
institution Nanyang Technological University
building NTU Library
continent Asia
country Singapore
Singapore
content_provider NTU Library
collection DR-NTU
topic DRNTU::Engineering::Mechanical engineering::Surgical assistive technology
spellingShingle DRNTU::Engineering::Mechanical engineering::Surgical assistive technology
Xiong, Fangli
Improvement on geometry and hemodynamics of coronary artery bypass grafting : numerical and experimental studies
description Impaired local hemodynamics associated with unfavorable anastomotic geometry has been implicated in the initiation and progression of intimal hyperplasia and atherosclerosis, the two vascular diseases for failing bypass anastomoses. Focused on the distal coronary anastomosis, this thesis seeks to determine critical hemodynamic wall parameters that indicate disease-susceptible sites as well as to optimize anastomotic geometry and hemodynamics pertaining to long-term graft viability. Numerical simulation and in vitro experimentation using Particle Image Velocimetry were employed to study pulsatile flows in coronary anastomotic models.
author2 Chong Chuh Khiun
author_facet Chong Chuh Khiun
Xiong, Fangli
format Theses and Dissertations
author Xiong, Fangli
author_sort Xiong, Fangli
title Improvement on geometry and hemodynamics of coronary artery bypass grafting : numerical and experimental studies
title_short Improvement on geometry and hemodynamics of coronary artery bypass grafting : numerical and experimental studies
title_full Improvement on geometry and hemodynamics of coronary artery bypass grafting : numerical and experimental studies
title_fullStr Improvement on geometry and hemodynamics of coronary artery bypass grafting : numerical and experimental studies
title_full_unstemmed Improvement on geometry and hemodynamics of coronary artery bypass grafting : numerical and experimental studies
title_sort improvement on geometry and hemodynamics of coronary artery bypass grafting : numerical and experimental studies
publishDate 2008
url https://hdl.handle.net/10356/5424
_version_ 1761781760800063488

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