Investigation on the mechanism of amyloid beta peptides oligomerization and the process for its inhibition

Amyloid beta (Abeta) plaque, which is a characteristic hallmark of Alzheimer’s disease (AD), results from the deposition of Abeta peptides. Amyloid beta peptides are prone to self assembly into high-order oligomers, which is the major pathological pathway of AD. It is generally believed that the Abe...

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Bibliographic Details
Main Author: Zhao, Li Na
Other Authors: Mu Yuguang
Format: Theses and Dissertations
Language:English
Published: 2013
Subjects:
Online Access:https://hdl.handle.net/10356/55043
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Institution: Nanyang Technological University
Language: English