Mapping interactions of filamin and migfilin : mechanism of inside-out signaling integrins.

• Main Author: Lu, Lewis Zhiping.
• Other Authors: Chua Geok Lin
• Format: Final Year Project
• Language: English
• Published: 2013
• Subjects: DRNTU::Science::Biological sciences::Biophysics
• Online Access: http://hdl.handle.net/10356/55046
• Institution: Nanyang Technological University

Integrin is a transmembrane heterodimer receptor that facilitates the connection of a cell to its environment. Integrin receptors are able to bind to both the extracellular environment as well as the internal cytoskeleton of the cell. Filamin A and Talin 1 are negative and positive regulators of int...