NMR approach to characterize Bcl-xl structure and interaction mechanism in membrane state
Bcl-2 family proteins play central roles in the apoptotic regulation at the mitochondrial membrane. Bcl-XL belongs to the anti-apoptotic subfamily of the Bcl-2 family. It interacts with pro-apoptotic subfamilies to inhibit them from forming pores on the mitochondrial membrane. Our current understand...
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Format: | Theses and Dissertations |
Language: | English |
Published: |
2014
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Online Access: | https://hdl.handle.net/10356/55292 |
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Institution: | Nanyang Technological University |
Language: | English |