Part 1: Synthesis of vinyl sulfones via palladium-catalyzed sulfonylation of olefins. Part 2: Trienes : Synthesis via C-H Functionalization and as precursors to complex molecules.

In Part 1, we would like to introduce a new protocol for the synthesis of vinyl sulfones via palladium-catalyzed sulfonylation of olefins using Pd(PhCN)2Cl2 (10 mol%) as a catalyst and K2CO3 (0.5 equiv) in dioxane. Both vinyl-pyridine and enamides were able to afford the corresponding products in mo...

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Main Author:	Wang, Wee Jian.
Other Authors:	Loh Teck Peng
Format:	Theses and Dissertations
Language:	English
Published:	2014
Subjects:	DRNTU::Science::Chemistry::Organic chemistry::Organic synthesis
Online Access:	http://hdl.handle.net/10356/55385
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Institution:	Nanyang Technological University
Language:	English

id	sg-ntu-dr.10356-55385
record_format	dspace
spelling	sg-ntu-dr.10356-553852023-02-28T23:44:35Z Part 1: Synthesis of vinyl sulfones via palladium-catalyzed sulfonylation of olefins. Part 2: Trienes : Synthesis via C-H Functionalization and as precursors to complex molecules. Wang, Wee Jian. Loh Teck Peng School of Physical and Mathematical Sciences DRNTU::Science::Chemistry::Organic chemistry::Organic synthesis In Part 1, we would like to introduce a new protocol for the synthesis of vinyl sulfones via palladium-catalyzed sulfonylation of olefins using Pd(PhCN)2Cl2 (10 mol%) as a catalyst and K2CO3 (0.5 equiv) in dioxane. Both vinyl-pyridine and enamides were able to afford the corresponding products in moderate to good yields using this novel method. Substituents are well tolerated in this reaction furnishing products which are potential useful intermediate that can be used for further transformation. Next in Part 2, we would like to present results from explorative studies on the synthesis of triene via C‒H functionalization and the transformation of trienes to complex molecules. Master of Science 2014-02-26T01:48:57Z 2014-02-26T01:48:57Z 2013 2013 Thesis http://hdl.handle.net/10356/55385 en 70 p. application/pdf
institution	Nanyang Technological University
building	NTU Library
continent	Asia
country	Singapore Singapore
content_provider	NTU Library
collection	DR-NTU
language	English
topic	DRNTU::Science::Chemistry::Organic chemistry::Organic synthesis
spellingShingle	DRNTU::Science::Chemistry::Organic chemistry::Organic synthesis Wang, Wee Jian. Part 1: Synthesis of vinyl sulfones via palladium-catalyzed sulfonylation of olefins. Part 2: Trienes : Synthesis via C-H Functionalization and as precursors to complex molecules.
description	In Part 1, we would like to introduce a new protocol for the synthesis of vinyl sulfones via palladium-catalyzed sulfonylation of olefins using Pd(PhCN)2Cl2 (10 mol%) as a catalyst and K2CO3 (0.5 equiv) in dioxane. Both vinyl-pyridine and enamides were able to afford the corresponding products in moderate to good yields using this novel method. Substituents are well tolerated in this reaction furnishing products which are potential useful intermediate that can be used for further transformation. Next in Part 2, we would like to present results from explorative studies on the synthesis of triene via C‒H functionalization and the transformation of trienes to complex molecules.
author2	Loh Teck Peng
author_facet	Loh Teck Peng Wang, Wee Jian.
format	Theses and Dissertations
author	Wang, Wee Jian.
author_sort	Wang, Wee Jian.
title	Part 1: Synthesis of vinyl sulfones via palladium-catalyzed sulfonylation of olefins. Part 2: Trienes : Synthesis via C-H Functionalization and as precursors to complex molecules.
title_short	Part 1: Synthesis of vinyl sulfones via palladium-catalyzed sulfonylation of olefins. Part 2: Trienes : Synthesis via C-H Functionalization and as precursors to complex molecules.
title_full	Part 1: Synthesis of vinyl sulfones via palladium-catalyzed sulfonylation of olefins. Part 2: Trienes : Synthesis via C-H Functionalization and as precursors to complex molecules.
title_fullStr	Part 1: Synthesis of vinyl sulfones via palladium-catalyzed sulfonylation of olefins. Part 2: Trienes : Synthesis via C-H Functionalization and as precursors to complex molecules.
title_full_unstemmed	Part 1: Synthesis of vinyl sulfones via palladium-catalyzed sulfonylation of olefins. Part 2: Trienes : Synthesis via C-H Functionalization and as precursors to complex molecules.
title_sort	part 1: synthesis of vinyl sulfones via palladium-catalyzed sulfonylation of olefins. part 2: trienes : synthesis via c-h functionalization and as precursors to complex molecules.
publishDate	2014
url	http://hdl.handle.net/10356/55385
_version_	1759855363951165440

Part 1: Synthesis of vinyl sulfones via palladium-catalyzed sulfonylation of olefins. Part 2: Trienes : Synthesis via C-H Functionalization and as precursors to complex molecules.

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