Molecular fluorescent probes for biological detection of hydrogen sulfide

This thesis is directed towards the development of hydrogen sulfide (H2S) probes, which includes their synthesis, an in-depth study on their fluorescence properties and potential applications. Both probe 37 and near infra-red (NIR) probe 39 were selective towards H2S in the presence of other bio...

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Main Author: Li, Eunice Yen Li
Other Authors: School of Physical and Mathematical Sciences
Format: Theses and Dissertations
Language:English
Published: 2014
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Online Access:http://hdl.handle.net/10356/55399
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Institution: Nanyang Technological University
Language: English
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spelling sg-ntu-dr.10356-553992023-02-28T23:33:43Z Molecular fluorescent probes for biological detection of hydrogen sulfide Li, Eunice Yen Li School of Physical and Mathematical Sciences Li Tianhu DRNTU::Science::Physics This thesis is directed towards the development of hydrogen sulfide (H2S) probes, which includes their synthesis, an in-depth study on their fluorescence properties and potential applications. Both probe 37 and near infra-red (NIR) probe 39 were selective towards H2S in the presence of other biologically relevant species but these probes could not differentiate between thiols and hydrogen sulfide. In addition, probe 37 was used to determine the H2S generation rate of GYY4137, a H2S donor of great medical importance. ​Master of Science 2014-02-26T04:36:46Z 2014-02-26T04:36:46Z 2013 2013 Thesis http://hdl.handle.net/10356/55399 en 69 p. application/pdf
institution Nanyang Technological University
building NTU Library
continent Asia
country Singapore
Singapore
content_provider NTU Library
collection DR-NTU
language English
topic DRNTU::Science::Physics
spellingShingle DRNTU::Science::Physics
Li, Eunice Yen Li
Molecular fluorescent probes for biological detection of hydrogen sulfide
description This thesis is directed towards the development of hydrogen sulfide (H2S) probes, which includes their synthesis, an in-depth study on their fluorescence properties and potential applications. Both probe 37 and near infra-red (NIR) probe 39 were selective towards H2S in the presence of other biologically relevant species but these probes could not differentiate between thiols and hydrogen sulfide. In addition, probe 37 was used to determine the H2S generation rate of GYY4137, a H2S donor of great medical importance.
author2 School of Physical and Mathematical Sciences
author_facet School of Physical and Mathematical Sciences
Li, Eunice Yen Li
format Theses and Dissertations
author Li, Eunice Yen Li
author_sort Li, Eunice Yen Li
title Molecular fluorescent probes for biological detection of hydrogen sulfide
title_short Molecular fluorescent probes for biological detection of hydrogen sulfide
title_full Molecular fluorescent probes for biological detection of hydrogen sulfide
title_fullStr Molecular fluorescent probes for biological detection of hydrogen sulfide
title_full_unstemmed Molecular fluorescent probes for biological detection of hydrogen sulfide
title_sort molecular fluorescent probes for biological detection of hydrogen sulfide
publishDate 2014
url http://hdl.handle.net/10356/55399
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