DNA I-motif : application to epigenetics and biosensing.

• المؤلف الرئيسي: Xu, Baochang
• مؤلفون آخرون: School of Physical and Mathematical Sciences
• التنسيق: Theses and Dissertations
• اللغة: English
• منشور في: 2014
• الموضوعات: DRNTU::Science::Chemistry::Analytical chemistry::Nucleic acids
• الوصول للمادة أونلاين: http://hdl.handle.net/10356/55448
• المؤسسة: Nanyang Technological University

DNA i-motif is an intercalated quadruplex structure formed by association of hemi- protonated C•CH+ pairs. The fact that i-motif folding sequences are widely present in oncogenic regions and human telomeric DNA suggests that the formation of i-motif may be associated with the regulation of oncogene...