Resistant machanisms, dynamic properties and inhibitor development of neuraminidase in influenza virus : molecular dynamics simulations studies

• Main Author: Han, Nanyu
• Other Authors: Mu Yuguang
• Format: Theses and Dissertations
• Language: English
• Published: 2014
• Subjects: DRNTU::Science::Biological sciences; DRNTU::Science::Biological sciences::Biophysics
• Online Access: http://hdl.handle.net/10356/55611
• Institution: Nanyang Technological University

Since the beginning of the last century, several pandemics with high morbidity and mortality caused by influenza viruses have occurred, and posed great threat to human life. Although vaccines and antiviral drugs have been developed to treat the upcoming influenza viruses, the accumulating mutant vir...