Mathematical model of activation of transforming growth factor - β1 with application to liver fibrosis progression
Transforming growth factor-β1 (TGF-β1) plays important roles in diverse cellular programs and extracellular activation of TGF-β1 from its latent form is an important stage in its physiological regulation. Plasmin has long been accepted as an activator of TGF-β1, but experimental data using in vivo f...
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| Format: | Theses and Dissertations |
| Language: | English |
| Published: |
2014
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| Online Access: | http://hdl.handle.net/10356/60570 |
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| Institution: | Nanyang Technological University |
| Language: | English |