Mathematical model of activation of transforming growth factor - β1 with application to liver fibrosis progression

• المؤلف الرئيسي: Venkatraman, Lakshmi
• مؤلفون آخرون: Sourav Saha Bhowmick
• التنسيق: Theses and Dissertations
• اللغة: English
• منشور في: 2014
• الموضوعات: DRNTU::Engineering::Computer science and engineering
• الوصول للمادة أونلاين: http://hdl.handle.net/10356/60570
• المؤسسة: Nanyang Technological University

Transforming growth factor-β1 (TGF-β1) plays important roles in diverse cellular programs and extracellular activation of TGF-β1 from its latent form is an important stage in its physiological regulation. Plasmin has long been accepted as an activator of TGF-β1, but experimental data using in vivo f...