Studying the role of protein deamidation in neurodegenerative disease in proteome-wide scale

Deamidation had been associated with amyloid-β peptide and tau protein aggregation in Alzheimer’s disease. Our previous study detected dysregulation of membrane proteins in vascular dementia, and a review of the data revealed extensive deamidation of Na+/K+- ATPase. Taken together, deamidation might...

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Bibliographic Details
Main Author: Ang, Yi Lin
Other Authors: Sze Siu Kwan
Format: Final Year Project
Language:English
Published: 2014
Subjects:
Online Access:http://hdl.handle.net/10356/60613
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Institution: Nanyang Technological University
Language: English