c-Abl, an accomplice in mutant p53 gain-of-function?
Accumulating evidence indicates that mutant p53 (mutp53) has further effects on cancer cells apart from causing the loss of wild type p53 (wtp53) tumour suppressor functions. The pro-metastatic functions of mutant p53 (mutp53) result in a worse prognosis and are often lethal. Although mutp53 is well...
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Format: | Final Year Project |
Language: | English |
Published: |
2014
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Online Access: | http://hdl.handle.net/10356/60624 |
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Institution: | Nanyang Technological University |
Language: | English |