c-Abl, an accomplice in mutant p53 gain-of-function?

Accumulating evidence indicates that mutant p53 (mutp53) has further effects on cancer cells apart from causing the loss of wild type p53 (wtp53) tumour suppressor functions. The pro-metastatic functions of mutant p53 (mutp53) result in a worse prognosis and are often lethal. Although mutp53 is well...

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Bibliographic Details
Main Author: Liu, Di
Other Authors: School of Biological Sciences
Format: Final Year Project
Language:English
Published: 2014
Subjects:
Online Access:http://hdl.handle.net/10356/60624
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Institution: Nanyang Technological University
Language: English