Butelase 1 : the fastest known ligase for protein cyclization and ligation

Peptide cyclization confers increased conformational stability and rigidity against metabolic and thermal denaturation. Encouraged by potential usage of cyclic peptides in the therapeutic applications, methods of protein cyclization and ligation have been developed such as native chemical ligation,...

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Bibliographic Details
Main Author: Chen, Shu Bee
Other Authors: Jimmy Pingkwan Tam @ James P Tam
Format: Final Year Project
Language:English
Published: 2014
Subjects:
Online Access:http://hdl.handle.net/10356/61748
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Institution: Nanyang Technological University
Language: English