Identifying the interaction between N-WASP, an actin nucleation factor and vinculin, a focal adhesion protein

N-WASP belongs to the WASP family of proteins which regulate actin cytoskeleton remodeling via the activation of Arp2/3 complex. Arp2/3 complex interacts with vinculin, an intracellular focal adhesion protein. Knockdown of N-WASP have shown to have reduced the levels of vinculin patches which could...

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Bibliographic Details
Main Author: Ganaesh
Other Authors: Thirumaran s/o Thanabalu
Format: Final Year Project
Language:English
Published: 2015
Subjects:
Online Access:http://hdl.handle.net/10356/62233
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Institution: Nanyang Technological University
Language: English