Engineering 3D thick porcine extracellular matrix for cardiac regeneration
This project focused on engineering a thick cardiac patch using an acellular scaffold derived from a porcine left ventricle as a possible replacement therapy for the scar tissue formed following acute heart damage. Whereas most studies demonstrated cardiac constructs with thicknesses up to a few hun...
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| Format: | Theses and Dissertations |
| Language: | English |
| Published: |
2015
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| Online Access: | https://hdl.handle.net/10356/62518 |
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| Institution: | Nanyang Technological University |
| Language: | English |
| Summary: | This project focused on engineering a thick cardiac patch using an acellular scaffold derived from a porcine left ventricle as a possible replacement therapy for the scar tissue formed following acute heart damage. Whereas most studies demonstrated cardiac constructs with thicknesses up to a few hundred micrometers, this project aims to recellularize an acellular scaffold with comparable thickness to the human native heart (1-1.2 cm). |
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