Engineering 3D thick porcine extracellular matrix for cardiac regeneration

This project focused on engineering a thick cardiac patch using an acellular scaffold derived from a porcine left ventricle as a possible replacement therapy for the scar tissue formed following acute heart damage. Whereas most studies demonstrated cardiac constructs with thicknesses up to a few hun...

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Main Author: Nguyen, Evelyne Bao-Vi
Other Authors: Marcelle Machluf
Format: Theses and Dissertations
Language:English
Published: 2015
Subjects:
Online Access:https://hdl.handle.net/10356/62518
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Institution: Nanyang Technological University
Language: English
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spelling sg-ntu-dr.10356-625182023-03-04T16:36:41Z Engineering 3D thick porcine extracellular matrix for cardiac regeneration Nguyen, Evelyne Bao-Vi Marcelle Machluf School of Materials Science & Engineering Technion-Israel Institute of Technology Subbu S. Venkatraman DRNTU::Engineering::Materials This project focused on engineering a thick cardiac patch using an acellular scaffold derived from a porcine left ventricle as a possible replacement therapy for the scar tissue formed following acute heart damage. Whereas most studies demonstrated cardiac constructs with thicknesses up to a few hundred micrometers, this project aims to recellularize an acellular scaffold with comparable thickness to the human native heart (1-1.2 cm). DOCTOR OF PHILOSOPHY (MSE) 2015-04-14T06:10:51Z 2015-04-14T06:10:51Z 2014 2014 Thesis Nguyen, E. B.-V. (2014). Engineering 3D thick porcine extracellular matrix for cardiac regeneration. Doctoral thesis, Nanyang Technological University, Singapore. https://hdl.handle.net/10356/62518 10.32657/10356/62518 en 215 p. application/pdf
institution Nanyang Technological University
building NTU Library
continent Asia
country Singapore
Singapore
content_provider NTU Library
collection DR-NTU
language English
topic DRNTU::Engineering::Materials
spellingShingle DRNTU::Engineering::Materials
Nguyen, Evelyne Bao-Vi
Engineering 3D thick porcine extracellular matrix for cardiac regeneration
description This project focused on engineering a thick cardiac patch using an acellular scaffold derived from a porcine left ventricle as a possible replacement therapy for the scar tissue formed following acute heart damage. Whereas most studies demonstrated cardiac constructs with thicknesses up to a few hundred micrometers, this project aims to recellularize an acellular scaffold with comparable thickness to the human native heart (1-1.2 cm).
author2 Marcelle Machluf
author_facet Marcelle Machluf
Nguyen, Evelyne Bao-Vi
format Theses and Dissertations
author Nguyen, Evelyne Bao-Vi
author_sort Nguyen, Evelyne Bao-Vi
title Engineering 3D thick porcine extracellular matrix for cardiac regeneration
title_short Engineering 3D thick porcine extracellular matrix for cardiac regeneration
title_full Engineering 3D thick porcine extracellular matrix for cardiac regeneration
title_fullStr Engineering 3D thick porcine extracellular matrix for cardiac regeneration
title_full_unstemmed Engineering 3D thick porcine extracellular matrix for cardiac regeneration
title_sort engineering 3d thick porcine extracellular matrix for cardiac regeneration
publishDate 2015
url https://hdl.handle.net/10356/62518
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