Characterization of Gib2 protein interactions in pathogenic fungus cryptococcus neoformans

• Main Author: Ng, Michelle Hui Ping
• Other Authors: Gao Yonggui
• Format: Final Year Project
• Language: English
• Published: 2015
• Subjects: DRNTU::Science::Biological sciences::Molecular biology
• Online Access: http://hdl.handle.net/10356/63145
• Institution: Nanyang Technological University

The canonical heterotrimeric G protein is comprised of α, β, and γ subunits. The fungal pathogen, Cryptococcus neoformans, encodes three α, one β, and two γ subunits. While the sole canonical β subunit, Gpb1, is involved in mating and haploid differentiation, Gib2 protein acts as an atypical β subun...