Investigating the human teashirt genes TSHZ2 and TSHZ3 in pancreatic and endocrine lineage commitment using genome modified human embryonic stem cells (hESC)
Pancreatic and Duodenal Homeobox 1 (PDX1) encodes a homeobox transcription factor expressed early in human embryonic pancreatic development. Loss of PDX1 results in complete pancreatic agenesis in both mice and man, indicating that it is a master regulator that coordinates the morphogenesis of this...
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| Format: | Final Year Project |
| Language: | English |
| Published: |
2015
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| Online Access: | http://hdl.handle.net/10356/63169 |
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| Institution: | Nanyang Technological University |
| Language: | English |
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