Investigating the human teashirt genes TSHZ2 and TSHZ3 in pancreatic and endocrine lineage commitment using genome modified human embryonic stem cells (hESC)

Pancreatic and Duodenal Homeobox 1 (PDX1) encodes a homeobox transcription factor expressed early in human embryonic pancreatic development. Loss of PDX1 results in complete pancreatic agenesis in both mice and man, indicating that it is a master regulator that coordinates the morphogenesis of this...

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Bibliographic Details
Main Author: Eng, Shermaine Zi Hui
Other Authors: Norris Ray Dunn
Format: Final Year Project
Language:English
Published: 2015
Subjects:
Online Access:http://hdl.handle.net/10356/63169
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Institution: Nanyang Technological University
Language: English

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