Protein-protein docking based on geometric complementarity

• المؤلف الرئيسي: Liu, Hui
• مؤلفون آخرون: Lee Yong Tsui
• التنسيق: Theses and Dissertations
• اللغة: English
• منشور في: 2015
• الموضوعات: DRNTU::Engineering::Computer science and engineering
• الوصول للمادة أونلاين: http://hdl.handle.net/10356/63342

Protein complex conformation prediction is crucial for studying the biological systems and thus for drug design. However it is very hard to do the prediction because of the flexibility of the backbone and side-chains of the receptor and ligand. In our work, the “divide and conquer” scheme has been u...