Protein-protein docking based on geometric complementarity

• Main Author: Liu, Hui
• Other Authors: Lee Yong Tsui
• Format: Theses and Dissertations
• Language: English
• Published: 2015
• Subjects: DRNTU::Engineering::Computer science and engineering
• Online Access: http://hdl.handle.net/10356/63342
• Institution: Nanyang Technological University

Protein complex conformation prediction is crucial for studying the biological systems and thus for drug design. However it is very hard to do the prediction because of the flexibility of the backbone and side-chains of the receptor and ligand. In our work, the “divide and conquer” scheme has been u...