Contribution of metabolic reprogramming to genome instability in cancer progression

• Main Author: Woo, Ren He
• Other Authors: Li Hoi Yeung
• Format: Final Year Project
• Language: English
• Published: 2015
• Subjects: DRNTU::Science::Biological sciences::Molecular biology
• Online Access: http://hdl.handle.net/10356/63813
• Institution: Nanyang Technological University

Alterations in cellular metabolism in tumor cells have been shown to regulate histone acetylation that enriches the expression of genes associated with cell proliferation. This provided the basis to the present study where it attempts to address if Akt-induced metabolic reprogramming promotes aberra...