Roles of CXCL1 and CXCL2 on neutrophils during immune complex-mediated inflammation

• 主要作者: Li, Jackson Liangyao
• 其他作者: Klaus Erik Karjalainen
• 格式: Theses and Dissertations
• 語言: English
• 出版: 2015
• 主題: DRNTU::Science::Biological sciences::Microbiology::Immunology; DRNTU::Science::Biological sciences::Molecular biology
• 在線閱讀: http://hdl.handle.net/10356/63953

CXCR2 is a critical regulator of neutrophil migration, and has been proposed to play an important role in immune complex-mediated inflammation. In the mouse, major pro-inflammatory CXCR2 ligands include CXCL1/KC/GRO-α and CXCL2/MIP-2a/GRO-β, but their specific individual roles on neutrophils have re...