Roles of CXCL1 and CXCL2 on neutrophils during immune complex-mediated inflammation

• Main Author: Li, Jackson Liangyao
• Other Authors: Klaus Erik Karjalainen
• Format: Theses and Dissertations
• Language: English
• Published: 2015
• Subjects: DRNTU::Science::Biological sciences::Microbiology::Immunology; DRNTU::Science::Biological sciences::Molecular biology
• Online Access: http://hdl.handle.net/10356/63953
• Institution: Nanyang Technological University

CXCR2 is a critical regulator of neutrophil migration, and has been proposed to play an important role in immune complex-mediated inflammation. In the mouse, major pro-inflammatory CXCR2 ligands include CXCL1/KC/GRO-α and CXCL2/MIP-2a/GRO-β, but their specific individual roles on neutrophils have re...