Three-dimensional co-culture of FRET based cancer cells and fibroblasts for modeling in vivo tumor

• Main Author: Kashmeena Parwyn Muruges
• Other Authors: Luo Qian, Kathy
• Format: Final Year Project
• Language: English
• Published: 2015
• Subjects: DRNTU::Engineering::Bioengineering
• Online Access: http://hdl.handle.net/10356/64850
• Institution: Nanyang Technological University

Three-dimensional (3D) in vitro cultures are known to recapitulate the physiological microenvironment present in in vivo tumors. The 3D spheroid model is an established model used in cancer research. However, the use of end-point assays in these studies do not allow for real-time analysis of tumorig...