Development of a FRET-based 3D in vitro breast tumor model and its application in evaluating drug-induced apoptosis
Tumorigenesis is a dynamic process involving growth, proliferation, heterotypic cell-cell and cell-ECM interactions and migration. Having traditionally relied on two-dimensional (2D) cultures for cancer research, it has been well-proven that these systems are unable to recapitulate the complexity an...
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格式: | Theses and Dissertations |
語言: | English |
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2017
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在線閱讀: | http://hdl.handle.net/10356/70579 |
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機構: | Nanyang Technological University |
語言: | English |