Development of a FRET-based 3D in vitro breast tumor model and its application in evaluating drug-induced apoptosis

Tumorigenesis is a dynamic process involving growth, proliferation, heterotypic cell-cell and cell-ECM interactions and migration. Having traditionally relied on two-dimensional (2D) cultures for cancer research, it has been well-proven that these systems are unable to recapitulate the complexity an...

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Bibliographic Details
Main Author: Anand, Padmaja
Other Authors: Teoh Swee Hin
Format: Theses and Dissertations
Language:English
Published: 2017
Subjects:
Online Access:http://hdl.handle.net/10356/70579
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Institution: Nanyang Technological University
Language: English