Structural biology of proteins involved in the replication of herpesviruses

• Main Author: Hew, Kelly Kai Li
• Other Authors: Nordlund, Pär
• Format: Theses and Dissertations
• Language: English
• Published: 2015
• Subjects: DRNTU::Science::Biological sciences::Microbiology::Virology; DRNTU::Science::Biological sciences::Biophysics; DRNTU::Science::Biological sciences::Biochemistry
• Online Access: http://hdl.handle.net/10356/65239
• Institution: Nanyang Technological University

Production of new infectious herpesvirus particles is dependent on the disruptions of host immune responses, herpesvirus DNA replication, assembly and reactivation from latency. To better understand herpesvirus replication, crystallographic and interaction studies were performed on several key prote...