Structural studies on hepatitis C virus (HCV) NS5A and its molecular interaction with CypA

• المؤلف الرئيسي: Lee, Jia Jun
• مؤلفون آخرون: Yoon Ho Sup
• التنسيق: Theses and Dissertations
• اللغة: English
• منشور في: 2015
• الموضوعات: DRNTU::Science::Biological sciences::Microbiology::Virology; DRNTU::Science::Biological sciences::Biochemistry
• الوصول للمادة أونلاين: http://hdl.handle.net/10356/65353

Hepatitis C virus infection is a worldwide issue and its NS5A protein interacts with host Cyclophilin A to play a crucial role in viral replication. To date, there is limited structural information for the intrinsically disordered NS5A protein. Here, low-resolution models of NS5A and NS5A-CypA from...