Use of a promiscuous biotin ligase to identify partners of the CRTC transcription factor
CREB is an important transcription factor that is regulated in part by the CRTC family of cofactors. CRTCs work in tandem with CREB to mediate various metabolic processes, such as promoting gluconeogenesis in response to increased glucagon levels. CRTC1 in particular is highly expressed in the brai...
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| 格式: | Final Year Project |
| 語言: | English |
| 出版: |
2015
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| 在線閱讀: | http://hdl.handle.net/10356/65366 |
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| 機構: | Nanyang Technological University |
| 語言: | English |