Uncovering the function of CREB regulated transcription coactivator 2 (CRTC2) in rodent brain

Uncovering the function of CREB regulated transcription coactivator 2 (CRTC2) in rodent brain

CRTC2 is potent transcriptional coactivator that undergoes robust nucleo-cytoplasmic shuttling to enhance CREB-mediated transcription in multiple cell types. In hepatocytes and pancreatic islet β-cells, CRTC2 responds to both glucose and incretin signals by activating CREB and upregulating the gen...

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Bibliographic Details
Main Author: Lim, Wei Lee
Other Authors: Ch’ng Toh Hean
Format: Thesis-Doctor of Philosophy
Language:English
Published: Nanyang Technological University 2018
Subjects:
DRNTU::Science::Biological sciences::Biochemistry
DRNTU::Science::Biological sciences::Molecular biology
Online Access:http://hdl.handle.net/10356/74944
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Institution: Nanyang Technological University
Language: English

Internet

http://hdl.handle.net/10356/74944

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