Uncovering the function of CREB regulated transcription coactivator 2 (CRTC2) in rodent brain

CRTC2 is potent transcriptional coactivator that undergoes robust nucleo-cytoplasmic shuttling to enhance CREB-mediated transcription in multiple cell types. In hepatocytes and pancreatic islet β-cells, CRTC2 responds to both glucose and incretin signals by activating CREB and upregulating the gen...

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書目詳細資料
主要作者: Lim, Wei Lee
其他作者: Ch’ng Toh Hean
格式: Thesis-Doctor of Philosophy
語言:English
出版: Nanyang Technological University 2018
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在線閱讀:http://hdl.handle.net/10356/74944
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