Uncovering the function of CREB regulated transcription coactivator 2 (CRTC2) in rodent brain
CRTC2 is potent transcriptional coactivator that undergoes robust nucleo-cytoplasmic shuttling to enhance CREB-mediated transcription in multiple cell types. In hepatocytes and pancreatic islet β-cells, CRTC2 responds to both glucose and incretin signals by activating CREB and upregulating the gen...
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| Format: | Thesis-Doctor of Philosophy |
| Language: | English |
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Nanyang Technological University
2018
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| Online Access: | http://hdl.handle.net/10356/74944 |
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| Institution: | Nanyang Technological University |
| Language: | English |