A loss-of-function study of CRTC1 in hippocampal neurons at basal state and during long-term synaptic plasticity
Encoding of long-term memory in neurons requires gene expression and protein synthesis. CREB, a well-characterised stimulus-induced transcription factor, is implicated in gene transcription supporting long-term plasticity. Several studies showed that CRTC1 is an important co-activator for CREB ac...
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Format: | Theses and Dissertations |
Language: | English |
Published: |
2019
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Online Access: | https://hdl.handle.net/10356/85237 http://hdl.handle.net/10220/49191 |
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Institution: | Nanyang Technological University |
Language: | English |