A loss-of-function study of CRTC1 in hippocampal neurons at basal state and during long-term synaptic plasticity

Encoding of long-term memory in neurons requires gene expression and protein synthesis. CREB, a well-characterised stimulus-induced transcription factor, is implicated in gene transcription supporting long-term plasticity. Several studies showed that CRTC1 is an important co-activator for CREB ac...

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Bibliographic Details
Main Author: Lim, Agnes Fang Yi
Other Authors: Ch’ng Toh Hean
Format: Theses and Dissertations
Language:English
Published: 2019
Subjects:
Online Access:https://hdl.handle.net/10356/85237
http://hdl.handle.net/10220/49191
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Institution: Nanyang Technological University
Language: English