System biology approach for functional annotation of the genome of human malaria parasite plasmodium falciparum and antimalarial drug discovery

• Main Author: Naw, Wah Wah
• Other Authors: Zbynek Bozdech
• Format: Theses and Dissertations
• Language: English
• Published: 2015
• Subjects: DRNTU::Science::Biological sciences
• Online Access: http://hdl.handle.net/10356/65593
• Institution: Nanyang Technological University

In this study, a gene co-expression network with a special focus on the P. falciparum exportome is constructed to annotate hypothetical proteins in P. falciparum. The project includes three sections: 1) transcriptional profiling of growth perturbations using 400 compounds in Malaria Box provided by...