Establishing a novel biochemical platform to reconstitute innate immune signalling events

NLR family, pyrin domain containing proteins (NLRPs) are a subset of intracellular pattern recognition receptors. NLRPs involved in inflammatory response are known to associate with the adaptor protein apoptosis-associated speck-like protein containing a CARD (ASC) to initiate inflammasome assembly....

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Bibliographic Details
Main Author: Koh, Chin Keat
Other Authors: Wu Bin
Format: Final Year Project
Language:English
Published: 2015
Subjects:
Online Access:http://hdl.handle.net/10356/65618
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Institution: Nanyang Technological University
Language: English