Structural study of ribosome : 1) structural basis of EF-G in translocation. 2) molecular mechanism of ribosome-dependent toxin YoeB in mRNA cleavage
During bacterial protein synthesis, elongation factor G (EF-G) facilitates the forward movement of the tRNA–mRNA by one codon, which is coupled to the ratchet-like movement of the ribosome and triggered by EF-G–mediated GTP hydrolysis. This process, known as translocation, is the most conserved part...
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Format: | Theses and Dissertations |
Language: | English |
Published: |
2015
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Online Access: | https://hdl.handle.net/10356/65648 |
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Institution: | Nanyang Technological University |
Language: | English |